Centre Hospitalier Universitaire Vaudois
Lead scientists: Giuseppe Pantaleo, Raphael Gottardo, Craig Fenwick
The Centre Hospitalier Universitaire Vaudois (CHUV), University of Lausanne, in Switzerland is a public non-profit institution dedicated to the improvement of human health through patient care, research and training, providing general hospital needs for the city of Lausanne and its area.
The Service of Immunology and Allergy, headed by Prof. Giuseppe Pantaleo, provides more than 5,400 outpatient consultations per year in the areas of allergy, chronic inflammatory diseases, and immunodeficiency. This research focuses on the identification of the immunological mechanisms linked to T lymphocytes, antiviral and mucosal immunity, immune tolerance in allergy and transplantation, with strong emphasis on translational research. Since the onset of the COVID-19 pandemic, the Vaccine and Immunotherapy Center (VIC) has established 3 longitudinal cohorts: ImmuCoV2, Post-COV and ImmunoVax. The CHUV Luminex Spike protein trimer assay developed by the service has been selected for a 90,000 population study in Switzerland.
The Biomedical Data Science Center, headed by Professor Raphael Gottardo, focuses on the development and application of new statistical and computational tools and methods to solve important biological problems through high-dimensional modeling and multimodal data integration. Research areas cover a wide range of topics such as the evaluation of vaccine immunogenicity, the characterization of immune responses to infectious diseases and cancer immunotherapies.
Roles in the COVICS project:
- Coordinator of the CoVICIS consortium
- Contribution to the cohort studies on targeted population (WP3)
- Co-lead of WP6 Immune Surveillance
- Lead of WP7 Data Science and Integration